Sign up Latest Topics

  Author   Comment  

Posts: 1
Reply with quote  #1 
Hello, I’ve recently had problems with my bladder where I’ll have to either go every few minutes or I won’t have to go for a while and my lower abdomen burns. I was recently given Oxybutynin to try and control it since my doctor found both acute and chronic cystitis in my bladder but I’m scared to take it since retention is a known side effect and I do keep a little in my bladder, about 21-30 ml on average. I just don’t want to get cathed again, I’m still traumatized from my cystoscopy. Can someone reassure me that taking this is the right thing to do or at least reassure me that if things do go south that I can just stop taking it and have things return to somewhat normal? For background, he wants me to take one before bed and one in the morning.

Posts: 1,863
Reply with quote  #2 
Hello Cruxis56

Welcome  to our Forum and hope you will find much to assist you.

I am sorry no one has been able answer you, it may help to type in the search above Oxybutynin, there are a few older posts.

You may also wish to become  a Member of BHUK as not only will you reieve a joining pack, but you will have access to so much more info then we can provide here.
I wonder if you have contacted these groups that may be nearer to you.

Interstitial Cystitis Association (ICA)
100 Park Avenue, Suite 108A
Rockville, MD 20850 USA
Tel: 800-HELP ICA (800-435-7422) 

Interstitial Cystitis Network ICN (National)
4983 Sonoma Highway, Suite L
Santa Rose, CA 95409, USA
Tel: 1-707-538.9442

Also this reply to another Member may also be of some extra help.
D Mannose
For those suffering with Gram Negative bugs (E coli, Proteus, Klebsiella and Pseudamonas), D Mannose has proved to be helpful in controlling a flare or preventing an attack from worsening or for post coital UTIs.
It works by clinging to the fingers of gram negative bugs, preventing them from attaching to the walls of the bladder and urethra. When you urinate, it helps to flush out the bugs from your system. Although it is a sugar, very little gets into the body and most is excreted through the kidneys and urine.

For more information, see the attached link.

Take a heaped teaspoon in water 4 times a day. Build up to 8 time a day when your bladder flares or every 2 hours including at night during an acute flare for 48 hours. The key is to make sure you have d-mannose in the bladder during the course of the day and night so that the e-coli is continually being flushed through.
You need to take the DM away from any acidic food or drink as it will counteract its effects and you need to keep your urine alkaline. Stools may be loose for a few days when first taking it.

Grapefruit Seed Extract
Grapefruit seed extract (GSE) is truly a broad-spectrum natural antibiotic, capable of killing a wide variety of
pathogens. Highly active against protozoa, bacteria, yeast and some viruses, it has been used for quite some time in the treatment of parasitic infections. It is nontoxic, generally hypoallergenic and can be administered for up to several months, which may be required to eliminate stubborn infections.

Please note that it can interfere with certain medications and if you are on blood thinning drugs you should not take anything containing Grapefruit. Check any natural medications with your GP or Pharmacist for contra-indications.

People using GSE should be aware that they may have, or may develop an allergy to this preparation. Persons with a known citrus allergy are at higher risk. Should you develop a rash or experience any other symptoms while using it, discontinue use immediately. As with antibiotics you should also take a good probiotic at the same time as the GSE will kill off the good microbiome in the gut so you need to repopulate.
Grapefruit Seed Extract – take 2 twice a day or 4-6 daily drops in water.

Oil of Oregano
Bacteria have one thing in common. They secrete a protein called urease. Scientists don’t completely know the exact mechanism. But, essentially, the urease that these bacteria make allows them to adhere to the epithelial cells. These are the cells lining the urinary tract. Without this ability to adhere to tissue, these bacteria would flush out of the kidneys and bladder every time we urinated. So if it were possible to block the way these bacteria were making urease, they would never be able to maintain an infection. And that’s where the oil of oregano comes in. Oregano contains active biological substances called phenols. These phenol compounds have the ability to stop bacteria from producing urease.

Many other herbs, such as cranberries and uva ursi also contain phenols but studies have shown that oregano has some of the strongest urease-inhibiting phenols. It works very well for Enterococus infections.

Oil of Oregano – take 2 twice a day or twice daily under the tongue.

I would personally try on of these at a time as they work on different type of bacteria. Eg D Mannose is great for E. coli and gram negative bacteria but does not work for gram positive. By adding all in at the same time you may confuse the picture

Tumeric and Marshamallow root are great for inflammation but MR is a diuretic so may make you go more. Try it in a tea and add Tumeric to hot milk. Pre relief will take the acidity out of foods and the calcium and magnesium tablets will help with your immune system and energy levels.

In terms of pain

Anti-histamines/Low histamine diets

Your bladder has the highest number of nerve endings of any organ in the body. When distressed, scared or upset, your body produces histamine and we often get that need to urinate sensation because the bladder’s nerve endings have been flooded by mast cells/histamine in the bladder and are now signaling you need to go (and this applies for people with perfectly healthy bladders). By taking an antihistamine you will reduce this sensation and also dial down the pain receptors that the nerve endings additionally produce (H1 and H2).

Most importantly histamine or mast cells are food to bacteria so by starving this food source, you prevent any active or planktonic bacteria in your bladder from feeding and multiplying and possibly setting up new infection colonies.

You can purchase Cetirizine and Ranitidine over the counter and these are commonly sold as allergy/antihistaminetablets. Atarax is a stronger anti-histamine but available on prescription only.
Some people are finding that a low histamine diet is also helping their bladder as many foods are high in histamine. To help in the early days of treatment you could look at a low histamine diet to see if it helps with symptoms. If so, stick with it but be warned, it is very restrictive.

Amitriptyline, Nortryptaline or Dosulepin are other options, these are low dose anti-depressants prescribed by your doctor that numb pain from the nerve endings in the bladder and can also help with those struggling to sleep. They should always be taken at night as they will make you feel drowsy. Alternatively, 5 HTP is a natural product containing serotonin and will help with mood and sleep.

Heat pads can offer great relief but provide the bacteria with a fantastic environment to breed and
flourish. For this reason, we advise using an ice pack between the legs, some chose to place ice on the vulva and urethral area. However, a heat pack placed on the back or lower abdomen can bring relief.

Pain relief is very individual and one size does not fit all. Discuss options with your specialist or GP. If needs be make an appointment with a Pelvic Pain clinic for further help. We will not recommend specific prescribed and controlled pain relief containing opiates in this forum as we are not medically trained.

Hope some of this helps and you get some relief soon.
Do keep posting and let us know your journey, as it will always br of help to others looking in.
Kind regards


Posts: 42
Reply with quote  #3 
Hi Cruxis56

I take Oxybutinin and have no issues with retention, although if I take lots of it it can make it difficult to pee. How much are you taking? I have 10mg a day when my symptoms are bad.

Posts: 9
Reply with quote  #4 
I also take Oxybutonin. I have a great GP who explained what it does etc. Basically it relaxes your bladder so it can hold more before you go.Since taking it I have found that sometimes I can't pee when I feel I want to.When this happens I do a basic breathing exercise so I don t go into panic mode, don't try to force it and remind myself it's doing what it is supposed to and just wait. After an hour or so I can happily pee.
I read the leaflet that came with the meds and was worried about getting retention but my GP said a smallish dosage would not cause retention and once it's out of your system you bladder would soon return to normal.I know that I have stopped taking it twice as I felt it was making it hard to go and within a day or two I've been peeing ok.

I can only tell you how it's affected me but I hope it helps.
Previous Topic | Next Topic

Quick Navigation:

Easily create a Forum Website with Website Toolbox.

This Forum is provided by Bladder Health UK and is intended as a place for Sufferers of Interstitial Cystitis, Bacterial Cystitis and Over Active Bladder, together with their family & friends to gather, online in a positive exchange.

BHUK is not a medical body & do not claim to have medical knowledge. It is not the intention of BHUK to provide specific medical advice, but to provide users with information to better understand their health & to manage their suffering.

Specific medical advice will not be provided & BHUK strongly advises that you consult your GP/Consultant/Urologist for professional advice.

We would hope that users of these forums will conduct themselves in a courteous and respectful manner. Any conduct not consistent with this standard will be deleted immediately and the poster may be restricted and/or terminated without warning.