Register Latest Topics
 
 
 


Reply
  Author   Comment  
Sarah1975

Registered:
Posts: 29
Reply with quote  #1 
Has anyone had a second broth culture done that showed the same bacteria (e coli and enterococcus in my case) but with different antibiotic resistances than the first time?  Originally the enterococcus was resistant to many of the abs I'd tried but this time it isn't.  The e coli on the other hand is now resistant to amoxicillin and it wasn't before.  I've never taken amoxicillin.  I'm about to start doxycycline, has anyone had any joy with this? looking at previous posts some have and some haven't.  I was on Nitro before and it helped with some symptoms but didn't touch the sharp stinging I get.
thanks all
Moderatorsusan

Moderator
Registered:
Posts: 1,042
Reply with quote  #2 
Yes that can easily happen - bacteria of the same family can be in different forms and react differently to antibiotics in terms of resistance. This could be a weak form of entero hence the fact its falling over to the ab in testing. The ecoli is almost certainly causing the stinging. Its an utter shark for pain, burning and generally feeling emotional, weepy and confused.

Doxycycline needs care - its very photo sensitive so always wear high factor sunscreen and try to stay in the shade. Its also quite hard on the stomach. Always always drink with a full glass of water and don't lie down immediately afterwards otherwise it can give you gastritis. Best to avoid taking it with dairy as well.

Also make sure you take a good high dose probiotic as you are wiping out the good guys as well as the bad guys in your stomach. Take at least 3 hours away from antibiotics although I'm sure Dr A has advised you of that.

Assume you have tried D Mannose powder for the ecoli? A teaspoon 4-6 times a day in water will help to flush out the coliform and reduce the stinging. Try not to urinate immediately afterwards and take before you go to bed so its in your system overnight.

Hope you feel better soon
suzyj

Registered:
Posts: 51
Reply with quote  #3 
Hello Sarah
I have been on doxycycline for 2/3 months and it was working just fine. I think that it is  now no longer working as well but it has been useful up to now. I originally took it last September as an anti malaria prophylactic (had been on nitro before that) and it got rid of the UTI but unfortunately after a virus in January it came back and I had several antibiotics which did not work before convincing a doctor to let me try doxy. As I said it was working but I am now getting symptoms again so am going to stop taking it and see what happens. Maybe I am now developing resistance to doxy I don;t know. Back to doctor tomorrow! I didn't have problems with photo sensitivity but I think prolonged use of any antibiotic will wear your body down.

I haven't done a broth culture but have done NHS and private tests - most NHS tests don't show anything much but the private ones have shown up ecoli mostly.  Good luck with the doxy
Sarah1975

Registered:
Posts: 29
Reply with quote  #4 
Hi both
Thanks so much for your responses.

Susan - thanks for the tips with taking Doxy.  The stinging is the worst issue for me now, it feels like it's at the bladder neck and is at it's most painful when my bladder contracts to tell me I need to go soon.  I have tried D Mannose, unfortunately I've not had much success with it, the stinging originally started whilst I was taking it along with Nitro when this infection started last year.  The other pain I had which was just at the end of peeing cleared up but the new pain, the stinging has stayed with me ever since.

Suzy - I'd previously read your post about using Doxy before and having some success, can you tell me how long you were taking it before you noticed a difference?  How did you get on at the Drs? Are you still taking Doxy or trying something else?
suzyj

Registered:
Posts: 51
Reply with quote  #5 
Hello Sarah - When I started doxy the first time symptoms were more or less under control with nitro but I didn't feel the underlying infection had gone. I stopped taking the nitro as soon as I started the doxy (which as I said was as an anti malaria prophylactic) so I noticed the difference quite quickly. I took it for about 6 weeks and I think it cleared up the infection. However, in January after a flu type virus the bladder problems/infection came back with worse symptoms than previously. To cut a long story short I saw several doctors who would not prescribe doxy despite the fact that I insisted that it had made a difference (it is not the normal treatment for UTIs...) and I had nitro (made it worse) and cephalexin (didn't do much) and finally I saw a 4th doctor who was open to suggestion and said that if it has worked before then it is worth trying again and he gave me about 2 months supply. By this time the problem had gone on for so long that the infection was (probably) embedded or whatever and it took 2 - 3 weeks for the doxy to really start working. I have just stopped taking it after about 3 months just to see what happens. So far it's OK but early days and I am not 100% sure it has completely gone. It is on repeat prescription so I am going to get that just in case.It was a struggle to get doxy as almost every doctor/urologist is insistent that this is not the first line of treatment for UTIs. Why don't they listen to the patient? Apart from that I take D mannose every night and turmeric supplement and have just started taking cordyceps supplement. I drink a lot of water, herb teas and not much else except coffee (which is fine)
Sarah1975

Registered:
Posts: 29
Reply with quote  #6 
Thanks for your reply Suzy.  When I was on Nitro, although I think it helped with the constant feeling of needing to go, it did irritate my urethra, in that it felt really sore up inside.  I've been on Doxy for a week and a half now and although I thought the last couple of days the stinging wasn't so bad it's been worse again today, I get the stinging every time my bladder signals I need to pee.  I have had these problems for getting on for a year now so I shouldn't expect a miracle overnight.  I feel your frustrations in that we as patients don't often get listened too.  After the initial confirmed infection that kicked this all off I kept going to GP's but because my samples were negative I didn't get anywhere until I was finally referred to a urologist who shrugged his shoulders when I explained all my symptoms and sent me away without any kind of help.
Amypip

Registered:
Posts: 20
Reply with quote  #7 
Hi I'm new to this forum and have had awful burning in my urethra 24/7, bladder cramps and painful kidneys since March this year. It has taken over my life and I feel suicidal with the constant pain and discomfort.

I have a numerous "normal" urine samples from my GP, had a normal cystoscopy which made the pains ten times worse and a normal ultrasound. The Consultant can only suggest more horrific invasive procedures like bladder biopsies and bladder stretching under GA. This screams out to me as totally unacceptable and going to makes things worse long term.

My body is telling me there is an infection of sorts in there and I need to find out where I can get more detailed urine tests done like broth cultures and tests for fastidious pathogens.

Please can someone ,tell me where I can get these done ?

Many thanks


Amy
Moderatorsusan

Moderator
Registered:
Posts: 1,042
Reply with quote  #8 
If you contact the Bladder Health Uk office on 0121 702 0820 they can give you further information.
Previous Topic | Next Topic
Print
Reply

Quick Navigation:

Easily create a Forum Website with Website Toolbox.


This Forum is provided by Bladder Health UK and is intended as a place for Sufferers of Interstitial Cystitis, Bacterial Cystitis and Over Active Bladder, together with their family & friends to gather, online in a positive exchange.

BHUK is not a medical body & do not claim to have medical knowledge. It is not the intention of BHUK to provide specific medical advice, but to provide users with information to better understand their health & to manage their suffering.

Specific medical advice will not be provided & BHUK strongly advises that you consult your GP/Consultant/Urologist for professional advice.

We would hope that users of these forums will conduct themselves in a courteous and respectful manner. Any conduct not consistent with this standard will be deleted immediately and the poster may be restricted and/or terminated without warning.